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Title page=0,1,4

TABLE OF CONTENTS=iv,5,2

LIST OF TABLES=vi,7,1

LIST OF FIGURE=vii,8,1

ABSTRACT=viii,9,2

[I.] INTRODUCTION=1,11,3

II. MATERIALS AND METHODS=4,14,1

A. Study Population=4,14,1

B. Measurement of Clinical Parameters=4,14,2

C. Laboratory Parameters=5,15,1

D. Methylenetetrahydrofolate reductase (MTHFR) C677T Genotype Analysis=6,16,2

E. Statistical Analysis=7,17,2

III. RESULTS=9,19,1

A. Baseline Characteristics of the study population=9,19,1

B. Distribution of the MTHFR C677T Genotype=10,20,2

C. Comparisons of Clinical and Laboratory parameters according to the MTHFR C677T Genotype (Table3)=12,22,2

D. Comparisons of Clinical and Laboratory Parameters according to the MTHFR C677T Mutation (Table4)=14,24,2

E. Correlation among Laboratory Parameters including Plasma BNP and Hcy Concentrations=16,26,1

F. Multiple Logistic Regression Analysis for Cardiovascular disease (Table5)=17,27,2

IV. DISCUSSION=19,29,5

V. CONCLUSION=24,34,1

REFERENCES=25,35,6

[summay in korean]=31,41,3

list of tables

Table1. Baseline Characteristics of the Study population=9,19,1

Table2. Distribution of the MTHFR C677T Genotype=10,20,1

Table3. Comparisons of Clinical and Laboratory Parameters According to the MTHFR C677T Genotype=13,23,1

Table4. Comparisons of Clinical and Laboratory Parameters according to the MTHFR C677T Mutation=15,25,1

Table5. Multiple Logistic Regression Analysis for Cardiovascular disease=18,28,1

list of figures

Fig1. The Electrophoresis of the Genotype of MTHFR C677T=11,21,1