Title Page
Abstract
Contents
Introduction 9
Materials and methods 11
Results 14
Discussion 22
Conclusion 23
References 24
국문요약 27
Figure 1. Inhibition of U14 cell line growth and migration by lenvatinib treatment.... 17
Figure 2. Lenvatinib anti-tumor activity in the U14 immunocompetent model. A, B). The U14 cell line was subcutaneously injected into immunocompetent... 18
Figure 3. Regulation of immune cells by lenvatinib in the U14 immunocompetent model.... 19
Figure 4. Synergistic anti-tumor activity of lenvatinib and anti-PD-1 in the U14 immunocompetent model.... 20
Figure 5. Regulation of immune cells in the TME by the synergistic anti-tumor activity of lenvatinib and anti-PD-1 in the U14 immunocompetent model.... 21