Title Page
Abstract
Contents
Introduction 8
Materials and Methods 10
1. Animal Models 10
2. Procedure for MCA Occlusion and Intracerebroventricular Injection 10
3. Neurological and Rotarod Test 11
4. MRI and Infarction Volume 12
5. Western Blot 13
6. Statistical analysis 14
Results 15
1. Behavioral Testing 15
2. MRI 15
3. Western Blot 16
Discussion 24
References 28
국문요약 34
Figure 1. Garcia score 17
Figure 2. Rotarod latency 18
Figure 3. Infarction volume changes 19
Figure 4. Changes in neuronal markers 20
Figure 5. Changes in apoptosis markers 21
Figure 6. Changes in pro-inflammatory markers 23