Title Page
Abstract
Contents
Ⅰ. Introduction 8
Ⅱ. Materials and Methods 12
1. Animals 12
2. Surgical procedures 13
3. Induction of experimental periodontitis and apical periodontitis 14
4. Histologic examination and histometric analysis 16
5. Statistical analysis 17
Ⅲ. Results 19
1. Clinical findings 19
2. Histologic findings 19
3. Histometric analyses 20
Ⅳ. Discussion 21
Ⅴ. Conclusion 27
Bibliography 38
국문초록 44
Table 1. BIC, BA, and IS-fBIC values 28
Figure 1. Experimental procedure 29
Figure 2. Clinical photos of the experimental procedure 30
Figure 3. Radiographs obtained before and after induction of experimental periodontitis and apical periodontitis 32
Figure 4. Methods for histometric analysis 34
Figure 5. Histologic images of all groups 37