Title Page
ABSTRACT
국문 초록
PREFACE
Contents
CHAPTER 1. INTRODUCTION 13
CHAPTER 2. MATERIALS AND METHODS 15
2.1. Zebrafish 15
2.2. MPTP Treatment 15
2.3. Drug Treatment 16
2.4. Locomotor Behavior Analysis 17
2.5. Quantification of Dopaminergic Neurons 18
2.6. Statistical Analysis 18
CHAPTER 3. RESULTS 19
3.1. Locomotor Behavior Analysis 19
3.2. Quantification of Dopaminergic Neurons 19
CHAPTER 4. DISCUSSION 20
CHAPTER 5. CONCLUSION 24
REFERENCES 25
Table 1. Locomotor behavior analysis for 20 minutes under light condition. 35
Figure 1. Schematic illustration of toxin and drug treatment for the neuro-restoration protocol 30
Figure 2. Zebrafish preparation for quantification of dopaminergic neurons 31
Figure 3. Locomotor behavior analysis for 20 minutes (min) under light conditions 32
Figure 4. Dopaminergic neuron quantification 33