Title Page
Abstract
Contents
I. Introduction 8
II. Methods 9
III. Results 11
IV. Discussion 14
V. References 18
국문초록 37
Table 1. Baseline characteristics of total cohort and comparison of permanent vs. non-permanent stoma formation groups 23
Table 2. Comparison of permanent stoma rates between treatment centres. 25
Table 3. Univariable and multivariable analyses of predictors of permanent stoma creation 26
Table 4. Subgroup analysis of predictors of abdominoperineal resection (n=89) 28
Table 5. Subgroup analysis of predictors of permanent stoma creation (n=55) after sphincter-preserving surgery (n=488) 30
Table 6. Comparison of baseline characteristics between permanent vs. non-permanent stoma formation groups for patients with pre-operative major incontinence (FISI ≥ 25) 32
Figure 1. Patient disposition. APR, abdominoperineal resection; Re-stoma, stoma recreation; SPS, sphincterpreserving surgery. 34
Figure 2. Aetiology of permanent stoma. 35
Figure 3. Kaplan-Meier plot of the cumulative incidence of permanent stoma creation from initial surgery according to aetiology. 36