표제지
목차
1. Introduction 11
1.1. 건강기능식품이란? 11
1.2. Microcapsule이란? 16
1.3. 연구 목적 19
2. Experimental 20
2.1. 시약 및 재료 20
2.2. 실험기구 및 분석 장비 20
2.3. 에멀젼 및 마이크로캡슐의 제조 21
3. Results and Discussion 23
3.1. 식물성 오일을 이용한 건강기능식품용 마이크로캡슐의 제조 및 응용 23
3.1.1. 에멀젼(Emulsion) 24
3.1.2. 마이크로캡슐(Microcapsule) 26
3.1.3. 파우더 제조 및 특성 평가 28
3.1.4. 마이크로캡슐 파우더 응용 32
3.2. 동물성 오일을 이용한 건강기능식품용 마이크로캡슐의 제조 및 응용 34
3.2.1. 에멀젼(Emulsion) 35
3.2.2. 마이크로캡슐(Microcapsule) 37
3.2.3. 파우더 제조 및 특성 평가 39
3.2.4. 지방산 함량 분석 43
4. Conclusion 44
참고문헌 45
ABSTRACT 48
Table 1. Ingredients with functioning properties for dietary supplements 13
Table 2. Preparation conditions of the emulsion and encapsulation 23
Table 3. Preparation conditions of tablets using microcapsules powders 32
Table 4. Preparation conditions of microcapsules with fish oil as core and β-cyclodextrin as shell materials. 34
Table 5. Changes of EPA and DHA contents after microencapsulation 43
Figure 1. Classification of food with general food, functional food, health functional food, and medicine. 11
Figure 2. The chemical structure of the three most important types of omega-3 fatty acids, (a) α-linolenic acid (ALA), (b) eicosapentanoic acid... 14
Figure 3. The chemical structure of the arabic gum and β-cyclodextrin. 15
Figure 4. Classification chart of the most important encapsulation techniques. 16
Figure 5. Schematic preparation of emulsion and microencapsulation to give functionality. 17
Figure 6. Morphology of various microcapsules. 18
Figure 7. Photos of the emulsion and microencapsulation process. 21
Figure 8. Photo and diagram of spray dryer to yield microcapsules powder in this study. 22
Figure 9. OM images of emulsion with Sacha-inchi oil as core materials. 24
Figure 10. DLS distribution of emulsion with Sacha-inchi oil as core materials. 25
Figure 11. OM images of microcapsule particles with Sacha-inchi oil-core and Arabic gum-shell materials. 26
Figure 12. DLS distribution of microcapsule particles with Sacha-inchi oil-core and Arabic gum-shell materials. 27
Figure 13. Photo of microcapsule powder with Sacha-inchi oil-core and Arabic gum-shell materials. 28
Figure 14. SEM images of microcapsule particles with Sacha-inchi oil-core and Arabic gum-shell materials. 29
Figure 15. TGA curve of microcapsules with Sacha-inchi oil-core and Arabic gum-shell materials. 30
Figure 16. DSC curve of microcapsules with Sacha-inchi oil-core and Arabic gum-shell materials. 31
Figure 17. Photos of the prepared tablets with the functionalized core-shell microcapsules. 33
Figure 18. OM images of emulsion with fish oil as core materials. 35
Figure 19. DLS distribution of emulsion with fish oil as core materials. 36
Figure 20. OM images of microcapsules with fish oil as core and β-cyclodextrin as shell materials. 37
Figure 21. DLS distribution of microcapsules with fish oil as core and β-cyclodextrin as shell materials. 38
Figure 22. Preparation of microcapsule powder with fish as core and β-cyclodextrin as shell materials after filteration. 39
Figure 23. SEM images of microcapsule powder with fish oil as core and β-cyclodextrin as shell materials after filteration. 40
Figure 24. TGA curve of microcapsule powder with fish oil as core and β-cyclodextrin as shell materials. 41
Figure 25. DSC curve of microcapsule powder with fish oil as core and β-cyclodextrin as shell materials. 42