표제지
목차
Abbreviation 8
요약 9
I. 서론 10
II. 연구 대상 및 방법 11
1. 연구 대상 11
1) 선정기준 11
2) 제외기준 11
3) 연구 대상자 산출 근거 11
2. 연구 방법 14
1) 대상자 모집 14
2) 한의변증 16
3) 무작위 배정 방법 및 할당 은닉 16
4) 중재 방법 16
5) 유효성 평가 기준 및 방법 17
6) 안전성 평가 17
7) 통계 분석 17
III. 결과 18
1. 연구 대상자 18
2. 연구 대상자의 일반적 특징 19
3. 연구 대상자의 부인과적 특징 20
4. 연구 대상자의 한의변증 22
5. 중재 전후 유효성 평가 변수 변화 23
1) 시각아날로그척도(Visual analogue scale, VAS) 23
2) 체표면 온도(Body temperature, BT) 26
3) 삶의 질 평가(WHOQOL-BREF) 36
4) 이상반응 40
5) 실험실 검사 41
IV. 고찰 42
V. 결론 46
참고문헌 48
부록 50
〈부록1〉 한의변증 설문지 50
〈부록2〉 [제목없음] 53
Abstract 56
Table 1. Study Flow of the Trial 15
Table 2. Intervention Flow of the Trial 16
Table 3. Baseline Characteristic of Groups 19
Table 4. Gynecological Characteristic of Groups in Menstruation 20
Table 5. Gynecological Characteristic of Groups in Leukorrhea 21
Table 6. Gynecological Characteristic of Groups in Parity and Coldness of Lower Abdomen 21
Table 7. Pattern Identification 22
Table 8. Coldness Visual Analogue Scale in Hands and Feet 24
Table 9. Body Temperature of Left LU4 and PC8 27
Table 10. Body Temperature of Right LU4 and PC8 28
Table 11. Body Temperature of Both LU4-PC8 29
Table 12. Body Temperature of Left ST32 and LR3 31
Table 13. Body Temperature of Right ST32 and LR3 32
Table 14. Body Temperature of Both ST32-LR3 33
Table 15. WHOQOL-BREF Score of Physical and Psychological Domain in Groups 37
Table 16. WHOQOL-BREF Score of Social and Environmental Domain in Groups 38
Table 17. WHOQOL-BREF Total Score in Groups 39
Table 18. Adverse Event of All Groups 40
Table 19. Relative Risk of Adverse Event on EA group and Control Group 40
Table 20. Relative Risk of Adverse Event on AC group and Control Group 40
Table 21. Laboratory test in Groups 41
Figure 1. Contactless Thermometer, Testo 835-T1, Lenzkirch, Germany 12
Figure 2. The Location of PC8 12
Figure 3. The Location of LU4 12
Figure 4. The Location of ST32 12
Figure 5. The Location of LR3 12
Figure 6. The Formula for Pooled Standard Deviation 13
Figure 7. The Formula for Estimating the Sample Size 13
Figure 8. Flow Chart of Clinical Trial 18
Figure 9. Changes in Visual Analogue Scale in groups 25
Figure 10. Changes in Body temperature in groups(V10-V1) 34
Figure 11. Changes in Body temperature in groups(V11-V1) 35