표제지

목차

I. Introduction 8

II. Material and Methods 13

III. Results 21

IV. Discussion 59

V. Conclusions 64

VI. References 66

Abstract 72

Table I. Formulation of normal diet and high fat diet 17

Table II. Contents of total polyphenol and total flavonoid in herbal mixture 22

Table III. DPPH free radical scavenging activity of various concentrations of herbal mixture 24

Table IV. Superoxide radical scavenging activity of various concentrations of herbal mixture 26

Table V. ABTS free radical scavenging activity of various concentrations of herbal mixture 28

Table VI. Hydroxyl radical scavenging activity of various concentrations of herbal mixture 30

Table VII. Reducing power of various concentrations of herbal mixture 32

Table VIII. Effect of herbal mixture on whole body and weight gain in high-fat diet induced obese mice 34

Table IX. Effect of herbal mixture on food intake and food efficacy ratio in high-fat diet induced obese mice 36

Figure 1. Effect of herbal mixture on the liver tissue weight in high-fat diet induced obese mice. The results are represent the... 38

Figure 2. Effect of herbal mixture on the adipocytes tissue weight in high-fat diet induced obese mice. The results are... 40

Figure 3. Effects of herbal mixture on the total cholesterol level in serum of high-fat diet induced obese mice. The results are... 42

Figure 4. Effects of herbal mixture on the HDL cholesterol level in serum of high-fat diet induced obese mice. The results are represent... 44

Figure 5. Effects of herbal mixture on the triglyceride level in serum of high-fat diet induced obese mice. The results are... 46

Figure 6. Effects of herbal mixture on the GOT and GPT level in serum of high-fat diet induced obese mice. The results are... 48

Figure 7. Effects of herbal mixture on the total cholesterol level in liver of high-fat diet induced obese mice. The results are... 50

Figure 8. Effects of herbal mixture on the triglyceride level in liver of high-fat diet induced obese mice. The results are... 52

Figure 9. Effects of herbal mixture on the total cholesterol level in feces of high-fat diet induced obese mice. The results are... 54

Figure 10. Effects of herbal mixture on the triglyceride level in feces of high-fat diet induced obese mice. The results are... 56

Figure 11. Hematoxylin and eosin-stained photomicrographs showing the epididymal adipose tissue(x100). (A) NC(normal... 58