Title Page
Contents
ABSTRACT IN KOREAN 8
I. INTRODUCTION 11
II. MATERIALS AND METHODS 15
2.1. Animals 15
2.2. In vivo model of endometriosis 15
2.3. Histological study 17
2.4. Immunohistochemistry study 17
2.5. RT-PCR for gene expression analysis 19
2.6. Western blotting for protein expression analysis 20
2.7. Statistical analysis 21
III. RESULTS 24
3.1. Gross findings of pelvic cavity 24
3.2. Histological study of endometriosis animal model 24
3.3. Immunohistochemistry data 25
3.4. Gene expression analysis by RT-PCR 25
3.5. Protein expression analysis by western blot 26
IV. DISCUSSION 37
V. CONCLUSION 41
REFERENCES 42
ABSTRACT IN ENGLISH 50
Table 1. Primer sequence set for amplify gene by RT-PCR 22
Table 2. The number of inflammatory lesion positive and no inflammatory... 28
Figure 1. Schematics showing procedures for preparing for the... 23
Figure 2. Abdomen area picture of anatomic procedure of the... 27
Figure 3. Histological images of endometriosis control, Dienogest,... 29
Figure 4. Light microscope images of immunohistochemical analysis with... 32
Figure 5. Analysis of gene expressions in the inflammatory lesion of... 35
Figure 6. Comparative analysis of protein expression in the inflammatory... 36