This study aims to investigate the anti-diabetic effects of Moondongumga and Hwanggitang.
In this experiment, Moondongumga and Hwanggitang extract were administrated in 3T3-L1 cells. And the accumulation of TG(Triglyceride) was measured using Oil Red-O staining and Elisa kit. Also, and the mRNA expression of Leptin, Adiponectin, PPAR-γ, and GLUT4 were observed using RT-PCR.
At the end of treatment, Moondongumga and Hwanggitang extract-treated group showed that fat accumulation in cells is suppressed.
In mRNA expression, Adiponectin, PPAR-γ, and Leptin that obesity-related factors were reduced, and GLUT4 that glucose-related factor was increased.