Title Page
Contents
Abstract 7
I. INTRODUCTION 9
II. MATERIALS AND METHODS 14
1. Patients and clinical assessment 14
2. MRI procedures 16
3. Genotyping 17
4. Statistical analysis 18
III. RESULTS 20
1. Sociodemographic and clinical characteristics of patients with PD 20
2. Genetic analysis 22
3. TBSS data 22
4. Correlation analysis 24
IV. DISCUSSION 26
V. CONCLUSION 31
REFERENCE 32
ABSTRACT IN KOREAN 37
Table 1. Sociodemographic and clinical characteristics of the patients with panic... 21
Table 2. Centered regions showing significant increases of fractional anisotropy... 24
Fig. 1. Schematic representation of the study: MR, Magnetic Resonance: PDSS,... 16
Fig. 2. Regions showing significant increases of FA values in NRPD compared to... 23
Fig. 3. Regions showing significant correlation between the ASI-R subscale scores... 25