표제지
목차
Abstract 9
I. 서론 13
II. 재료 및 방법 20
1. 실험 재료 20
2. 표준품 및 시약 20
3. 표준 용액 제조 23
4. 비스페놀 분석방법 23
4.1. 시료 전처리 23
4.2. 기구 26
4.3. 기기 분석 26
III. 결과 및 고찰 30
1. 직선성 30
2. 검출한계 및 정량한계 30
3. 회수율 35
4. 유통중인 영·유아용 기구 용기에서의 비스페놀류 화합물 잔류 현황 분석 38
5. 비스페놀류 화합물의 분석에 대한 국내외 동향 및 향후 과제 43
IV. 요약 47
V. 참고문헌 49
Table 1. HPLC-FLD conditions used in the determination of bisphenols 27
Table 2. HPLC-FLD conditions used in the determination of bisphenol A diglycidyl... 28
Table 3. UPLC-MS/MS conditions used in the determination of bisphenols 29
Table 4. The linearity of bisphenol A (BPA), bisphenol A diglycidyl ether... 31
Table 5. The limit of detection (LOD) and limit of quantification (LOQ) of... 36
Table 6. The recovery of bisphenol A (BPA), bisphenol A diglycidyl ether... 37
Fig. 1. Structure of bisphenol. 14
Fig. 2. Molecular structures of bisphenol A and their decomposition products... 15
Fig. 3. Molecular structures of bisphenol F and their decomposition products... 16
Fig. 4. Classification of infant containers samples according to the materials. ABS,... 21
Fig. 5. Classification of infant containers samples according the origin. 22
Fig. 6. Flow bisphenol A, bisphenol A diglycidyl ether and bisphenol F diglycidyl... 24
Fig. 7. Calibration curves of phenol, bisphenol A (BPA) and p-tert-butylphenol. 32
Fig. 8. Calibration curves of bisphenol F diglycidyl ether (BFDGE), bisphenol F... 33
Fig. 9. Calibration curves of bisphenol A diglycidyl ether (BADGE), bisphenol A... 34
Fig. 10. HPLC-FLD chromatograms of bisphenol F bis (2,3-dihydroxypropyl)... 39
Fig. 11. LC-MS/MS chromatograms of bisphenol F bis (2,3-dihydroxypropyl) ether... 42