표제지
목차
I. 緖論 8
II. 材料 및 方法 11
1. 材料 11
(1) 實驗動物 11
(2) 試料의 준비 11
(3) 試驗裝置 11
(4) 試驗物質 12
2. 方法 13
(1) 檢液의 調製 13
(2) 행동약리학적 연구 13
3. 統計處理 19
III. 實驗結果 20
1. Elevated Plus-maze에서 녹용 추출물의 항불안 효과 20
2. Locomotor activity test 23
3. Forced swimming test (FST)를 통한 녹용 추출물의 항우울 작용 확인 26
4. Tail suspension test를 통한 녹용 추출물의 항우울 작용 확인 28
IV. 考察 30
V. 結論 35
參考文獻 37
국문초록 42
ABSTRACT 44
Table 1. Time spent in the behaviors shown by mice exploring the elevated plus-maze (mean ± S.E.M.) 21
Table 2. Effects of Cervi Pantotrichum on exploratory behavior of mice in the open field test 24
Figure 1. Elevated Plus-maze 15
Figure 2. Open field test 16
Figure 3. Forced swimming test 18
Figure 4. Tail suspension test 19
Figure 5. Effect of a single treatment of the Cervi Pantotrichum on the percentage of the time spent in open arms and the number of entries in to open arms of the elevated plus-maze... 22
Figure 6. The effect of Cervi Pantotrichum on the locomotor activity in the open field test over 5 min test in mice. Each bar represents mean ± S.E.M obtained from 8-10 mice.... 25
Figure 7. Anti-depressive effect of single treatment with Cervi Pantotrichum on the forced swimming test in mice. C. Pantotrichum was orally treated 1 h prior to the test at... 27
Figure 8. Anti-depressive effect of single treatment with Cervi Pantotrichum on the tail suspension test in mice. C. Pantotrichum was orally treated 1 h prior to the test at... 29