Title Page
국문초록
Contents
I. Introduction 10
II. Materials and Methods 12
1. Materials 12
2. Cell culture 12
3. Apoptosis evaluation 13
4. Western blot analysis 13
5. Statistical analysis 14
III. Results 15
1. Induction of apoptosis 15
2. Expression of apoptosis regulatory proteins 18
IV. Discussion 25
References 28
ABSTRACT 34
Table I. Effect of BV on apoptosis in DU-145 cells 16
Table II. Effect of BV on expression of Bax, PARP, Cleaved caspase-3 and -9 in DU-145 cells 21
Table III. Effect of BV on expression of Bcl-2, p-AKT, AKT, XIAP, cIAP2, MMP2 and MMP13 in DU-145 cells 23
Fig. 1. Effect of BV on induction of apoptosis of DU-145 cells 17
Fig. 2. Effect of BV on expression of Bax and Bcl-2 in DU-145 cells 20
Fig. 3. Effect of BV on expression of pro-apoptotic Proteins in DU-145 cells 22
Fig. 4. Effect of BV on expression of anti-apoptotic proteins in DU-145 cells 24