The purpose of this research was to study the effects of resistance exercise using water bottles and pilates exercise on atherosclerosis indices and inflammation related markers in elderly obese women. The subjects of this research were elderly obese women aged over 65 without any metabolic diseases and haven’t had regular and vigorous physical activities. The subjects were divided into two groups of resistance exercise using water bottles and pilates exercise group(12 subjects) and a non-exercise control group(12 subjects). The subjects in resistance exercise using water bottles and pilates exercise group performed resistance exercise using water bottles at 8-12 repetions of exercise intensity for 20 minutes and pilates exercise at RPE 10-13(10-12 repetions) of exercise intensity for 20 minutes, 60 minutes a day for 3 days a week during 12 weeks. All subjects of this study were examined the changes in atherosclerosis indices and inflammation related markers. The results of the study in the elastic band and pilates exercise group were as follows; The body fat(%), TG, TC, LDL-C, TC/HDL-C, TG/HDL-C, Fibrinogen, CRP had significantly decreased. It was concluded resistance exercise using water bottles and pilates exercise group had positive effects on atherosclerosis indices and inflammation related markers to in elderly obese women. Therefore, resistance exercise using water bottles and pilates mat is effective in the management of vascular inflammation, obesity and elderly women, and this is the form of exercise is effective in preventing cardiovascular diseases.