Contents
NO/cGMP pathway is involved in exocrine secretion from rat pancreatic acinar cells / Seong Hoon Ahn ; Dong-Wan Seo ; Young-Kwon Ko ; Dae-Suk Sung ; Gyu-Un Bae ; Jong-Woo Yoon ; Sung-Youl Hong ; Jeung-Whan Han ; Hyang-Woo Lee 1
[요약] 1
Introduction 1
Materials and methods 2
Materials 2
Experimental animals and cell isolation 2
Amylase assay 2
NOS assay ([³H]citrulline accumulation) 2
NO analysis 3
Determination of cGMP 3
Pretreatment of rat pancretic acinar cells with MMA 3
Statistical analysis 3
Results 3
Isolation of rat pancreatic acinar cells 3
Effect of MMA on exocrine secretion from rat pancreatic acinar cells stimulated with CCK-OP 3
Effect of time course on the cGMP levels in rat pancreatic acinar cells in the absence or presence of CCK-OP 4
Effect of time course on the amylase release in rat pancreatic acinar cells 5
Discussion 6
Acknowledgments(Acknowlegements) 6
References cited 6