표제지
목차
I. 서론 12
II. 재료 14
1. 재료 및 기기 14
1) 재료 14
2) 실험에 사용된 기기 15
III. 실험방법 16
1. 에멀젼 제조 방법 16
1) 고온유화법을 이용한 에멀젼 제조 방법 16
2) D상유화법을 이용한 에멀젼 제조 방법 20
3) D상유화법을 적용한 오일 종류별로 사용한 3가지 계면활성제의 조합 23
2. 이온성 계면활성제인 SODIUM STEAROYL GLUTAMATE의 사용유무에 따른 변화 32
3. 안정성 평가 34
1) 위상차현미경을 이용한 입자크기와 균일도 평가 34
2) 점도 측정 34
3) 온도별 장기보관 안정성 평가 35
IV. 결과 및 고찰 36
1. 고온유화법과 D상유화법을 이용한 에멀젼 형성 비교 및 안정성 평가 36
1) 비극성오일 - SQUALANE 36
2) 극성오일 - CETYL ETHYLHEXANOATE 51
2. D상유화법을 적용한 오일별로 사용한 3가지 계면활성제의 조합 실험 65
1) 비극성오일 65
2) 극성오일 85
3) 계면활성제에 따른 오일별 입자크기 비교 105
3. 이온성 계면활성제인 SODIUM STEAROYL GLUTAMATE의 사용유무에 따른 변화 109
V. 결론 114
VI. 참고문헌 116
초록 117
Abstract 118
Table 1. The experimental formulation (A1~A3) as the kinds of surfactants variation of the... 18
Table 2. The experimental formulation (B1~B3) as the kinds of surfactants variation of the... 19
Table 3. The experimental formulation (C1~C3) as the kinds of surfactants variation of the... 21
Table 4. The experimental formulation (D1~D3) as the kinds of surf act ants variation of the... 22
Table 5. The experimental formulation (AA~AC) as the kinds of surfactants variation of the... 24
Table 6. The experimental formulation (BA~BC) as the kinds of surfactants variation of the... 25
Table 7. The experimental formulation (CA~CC) as the kinds of surfactants variation of the... 26
Table 8. The experimental formulation (DA~DC) as the kinds of surfactants variation of the... 27
Table 9. The experimental formulation (EA~EC) as the kinds of surfactants variation of the... 28
Table 10. The experimental formulation (FA~FC) as the kinds of surfactants variation of the... 29
Table 11. The experimental formulation (GA~GC) as the kinds of surfactants variation of the... 30
Table 12. The experimental formulation (HA~HC) as the kinds of surfactants variation of the... 31
Table 13. The experimental formulation (I1~I3) as the kinds of surfactants variation of the... 33
Table 14. Properties of SQUALANE. 66
Table 15. Properties of LIQUID PARAFFIN. 71
Table 16. Properties of HYDROGENATED DIDECENE. 76
Table 17. Properties of ISOHXADECANE. 81
Table 18. Properties of CETYL ETHYLHEXANOATE. 86
Table 19. Properties of CAPRYLIC/CAPRIC TRIGLYCERIDE. 91
Table 20. Properties of 2-OCTYLDODECANOL. 96
Table 21. Properties of C12-15 ALKYL BENZOATE. 101
Table 22. Figure of average particle size of all kind of oils as using three surfactants.... 108
Table 23. Properties of SODIUM STEAROYL GLUTAMATE. 111
Figure 1. Process drawing of Direct Emulsification formulation. 17
Figure 2. Process drawing of D Phase formulation. 20
Figure 3. Microscope image of particle size of experimental formulation A1~A3.... 38
Figure 4. Microscope image of particle size of experimental formulation A1 after 3day.... 38
Figure 5. Microscope image of particle size of experimental formulation A1 after 7day.... 38
Figure 6. Viscosity measurement of experimental formulation A1 during 1 week. 39
Figure 7. Microscope image of particle size of experimental formulation A2 after 3day... 40
Figure 8. Microscope image of particle size of experimental formulation A2 after 7day... 40
Figure 9. Viscosity measurement of experimental formulation A2 during 1 week. 41
Figure 10. Microscope image of particle size of experimental formulation A3 after 3day... 42
Figure 11. Microscope image of particle size of experimental formulation A3 after 7day... 42
Figure 12. Viscosity measurement of experimental formulation A3 during 1 week. 43
Figure 13. Microscope image of particle size of experimental formulation C1~G3.... 45
Figure 14. Microscope image of particle size of experimental formulation C1 after 3day... 45
Figure 15. Microscope image of particle size of experimental formulation C1 after 3day... 45
Figure 16. Viscosity measurement of experimental formulation C1 during 1 week. 46
Figure 17. Microscope image of particle size of experimental formulation C2 after 3day... 47
Figure 18. Microscope image of particle size of experimental formulation C2 after 7day... 47
Figure 19. Viscosity measurement of experimental formulation C2 during 1 week. 48
Figure 20. Microscope image of particle size of experimental formulation C3 after 3day... 49
Figure 21. Microscope image of particle size of experimental formulation C3 after 7day... 49
Figure 22. Viscosity measurement of experimental formulation C3 during 1 week. 50
Figure 23. Microscope image of particle size of experimental formulation B1~B3.... 52
Figure 24. Microscope image of particle size of experimental formulation B1 after 3day... 52
Figure 25. Microscope image of particle size of experimental formulation B1 after 7day... 52
Figure 26. Viscosity measurement of experimental formulation B1 during 1 week. 53
Figure 27. Microscope image of particle size of experimental formulation B2 after 3day... 54
Figure 28. Microscope image of particle size of experimental formulation B2 after 7day... 54
Figure 29. Viscosity measurement of experimental formulation B2 during 1 week. 55
Figure 30. Microscope image of particle size of experimental formulation B3 after 3day... 56
Figure 31. Microscope image of particle size of experimental formulation B3 after 7day... 56
Figure 32. Viscosity measurement of experimental formulation B3 during 1 week. 57
Figure 33. Microscope image of particle size of experimental formulation D1~D3.... 59
Figure 34. Microscope image of particle size of experimental formulation D1 after 3day... 59
Figure 35. Microscope image of particle size of experimental formulation D1 after 7day... 59
Figure 36. Viscosity measurement of experimental formulation D1 during 1 week. 60
Figure 37. Microscope image of particle size of experimental formulation D2 after 3day... 61
Figure 38. Microscope image of particle size of experimental formulation D2 after 7day... 61
Figure 39. Viscosity measurement of experimental formulation D2 during 1 week. 62
Figure 40. Microscope image of particle size of experimental formulation D3 after 3day... 63
Figure 41. Microscope image of particle size of experimental formulation D3 after 7day... 63
Figure 42. Viscosity mD1surement of experimental formulation D3 during 1 week. 64
Figure 43. Microscope image of particle size of counting ten of experimental formulation... 67
Figure 44. Microscope image of particle size of counting ten of experimental formulation AA~AC. 68
Figure 45. Viscosity measurement of experimental formulation AA~AC. 69
Figure 46. Microscope image of particle size of counting ten of experimental formulation BA~BC... 72
Figure 47. Microscope image of particle size of counting ten of experimental formulation BA~BC. 73
Figure 48. Viscosity measurement of experimental formulation BA~BC. 74
Figure 49. Microscope image of particle size of counting ten of experimental formulation CA~CC... 77
Figure 50. Microscope image of particle size of counting ten of experimental formulation CA~CC. 78
Figure 51. Viscosity measurement of experimental formulation CA~CC. 79
Figure 52. Microscope image of particle size of counting ten of experimental formulation... 82
Figure 53. Microscope image of particle size of counting ten of experimental formulation DA~DC. 83
Figure 54. Viscosity measurement of experimental formulation DA~DC. 84
Figure 55. Microscope image of particle size of counting ten of experimental formulation EA~EC... 87
Figure 56. Microscope image of particle size of counting ten of experimental formulation EA~EC. 88
Figure 57. Viscosity measurement of experimental formulation EA~EC. 89
Figure 58. Microscope image of particle size of counting ten of experimental formulation FA~FC... 92
Figure 59. Microscope image of particle size of counting ten of experimental formulation FA~FC. 93
Figure 60. Viscosity measurement of experimental formulation FA~FC 94
Figure 61. Microscope image of particle size of counting ten of experimental formulation... 97
Figure 62. Microscope image of particle size of counting ten of experimental formulation GA~GC. 98
Figure 63. Viscosity measurement of experimental formulation GA~GC. 99
Figure 64. Microscope image of particle size of counting ten of experimental formulation... 102
Figure 65. Microscope image of particle size of counting ten of experimental formulation HA~HC. 103
Figure 66. Viscosity measurement of experimental formulation HA~HC. 104
Figure 67. Image of average particle size of all kind of oils as using three surfactants.... 107
Figure 68. Image experimental formulation I1, I2, I3 during 7 days. 112
Figure 69. Microscope image of particle size of experimental formulation I1.... 113
Figure 70. Microscope image of particle size of experimental formulation I3.... 113