Title Page
Contents
Abstract 6
Introduction 8
Materials & Methods 10
1. Subjects. 10
2. DNA extraction. 10
3. HLA-A,-B,-C, and DRB1 genotyping. 10
4. Statistical analysis. 11
Results 13
Discussion 22
References 26
초록 33
TABLE 1. Allele frequencies of HLA-A in patients with AITD and the control group. 16
TABLE 2. Allele frequencies of HLA-B in patients with AITD and patients in the control group. 17
TABLE 3. Allele frequencies of HLA-C in the patients with AITD and the control group. 18
TABLE 4. Allele frequencies of HLA-DRB1 in the patients with AITD and the control group. 19
TABLE 5. Relative strength of the associations of HLA-B*46 and -Cw*01 with autoimmune thyroid diseases. 20
TABLE 6. Relative strength of the associations of with HLA-B*46 and -DRB1*08 with autoimmune thyroid diseases. 21