표제지
감사의 글
목차
Abstract 6
Introduction 7
Materials & Methods 9
Preparation of PM2.5 9
Cell culture and treatments 10
ROS measurement by chemiluminescence assay 10
Reverse transcription-PCR (RT-PCR) 11
Western blotting analyses for IxB 11
Luciferase reporter assay 12
Cytokine assay 12
Statistical analysis 12
Results 13
Production of ROS in lung epithelial cells 13
PM2.5 induced NFκB activation by IκBα degradation 14
Antioxidants or iNOS inhibitor inhibited the PM2.5-induced IκBα degradation 15
The iNOS inhibitor inhibited the PM2.5-mediated IL-8 expression and NFκB activity 15
Discussion 22
References 26
영문논문제출서 30
영문인준서 31
초록 32